Elevated substance P levels in HIV-infected women in comparison to HIV-negative women
Submitted by dcc on Wed, 04/23/2014 - 7:47am
Title | Elevated substance P levels in HIV-infected women in comparison to HIV-negative women |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Douglas, SD, Cnaan, A, Lynch, KG, Benton, T, Zhao, H, Gettes, DR, Evans, DL |
Journal | AIDS Research and Human Retroviruses |
Volume | 24 |
Pagination | 375-8 |
Date Published | 2008 |
Keywords | Adolescent, Adult, Aged, External, Female, HIV Infections, Humans, Middle Aged, Substance P |
Abstract | Substance P and its receptor (neurokinin-1R) are potent modulators of neuroimmunoregulation and HIV/AIDS infection. We previously demonstrated that HIV-seropositive men had significantly higher substance P levels compared to uninfected controls. We now demonstrate that substance P plasma levels are significantly higher in HIV-infected women in comparison to uninfected control women. |
URL | http://www.ncbi.nlm.nih.gov/pubmed/18327973 |