Home /Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia.

Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia.

Submitted by dcc on Wed, 06/14/2023 - 4:15pm
TitleCasein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia.
Publication TypeJournal Article
Year of Publication2023
AuthorsOhene-Nyako, M, Nass, SR, Richard, HT, Lukande, R, Nicol, MR, McRae, M, Knapp, PE, Hauser, KF
JournalASN Neuro
Volume15
Pagination17590914231158218
Date Published2023 Jan-Dec
ISSN1759-0914
KeywordsExternal
Abstract

HIV/HIV-1 Tat and morphine independently increase pathologic phosphorylation of TAR DNA binding protein 43 in the striatum. HIV- and opioid-induced pathologic phosphorylation of TAR DNA binding protein 43 may involve enhanced CK2 activity and protein levels.
DOI10.1177/17590914231158218
Alternate JournalASN Neuro
PubMed ID36890725
PubMed Central IDPMC9998424
Grant ListU24 MH100925 / MH / NIMH NIH HHS / United States
U24 MH100931 / MH / NIMH NIH HHS / United States
F32 DA053163 / DA / NIDA NIH HHS / United States
R01 DA045588 / DA / NIDA NIH HHS / United States
R01 DA034231 / DA / NIDA NIH HHS / United States
R01 DA057346 / DA / NIDA NIH HHS / United States
U24 MH100930 / MH / NIMH NIH HHS / United States