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A case of primary HIV type 1 and cytomegalovirus coinfection presenting with widespread clinical disease.

Submitted by dcc on Wed, 06/16/2021 - 10:13am
TitleA case of primary HIV type 1 and cytomegalovirus coinfection presenting with widespread clinical disease.
Publication TypeJournal Article
Year of Publication2014
AuthorsKim, JY, Singer, EJ, Bonelli, L, Klausner, JD
JournalJ Int Assoc Provid AIDS Care
Volume13
Issue3
Pagination196-9
Date Published2014 May-Jun
ISSN2325-9574
KeywordsAdult, Alanine Transaminase, Anti-Retroviral Agents, Aspartate Aminotransferases, Coinfection, Cytomegalovirus Infections, Drug Therapy, Combination, External, Fever, Fundus Oculi, Hepatitis B Antibodies, HIV Infections, HIV-1, Humans, Hypesthesia, Male, Meningitis, Viral, Paresthesia, Retinal Diseases
Abstract

Coinfection of HIV-1 and cytomegalovirus (CMV) may occur given the shared routes of transmission, and the clinical presentations of each process overlap. We present a case of acute HIV-1 and CMV coinfection presenting with an acute febrile illness complicated by meningitis, hepatitis, and retinopathy. This and other similar cases demonstrate the need to consider CMV coinfection in acute HIV-1 disease, particularly in situations with significant end-organ damage.
DOI10.1177/2325957413519289
Alternate JournalJ Int Assoc Provid AIDS Care
PubMed ID24476962
PubMed Central IDPMC4361025
Grant ListU24 MH100929 / MH / NIMH NIH HHS / United States
U01 MH083500 / MH / NIMH NIH HHS / United States
UL1 TR000124 / TR / NCATS NIH HHS / United States
P30 MH058107 / MH / NIMH NIH HHS / United States
P30 AI028697 / AI / NIAID NIH HHS / United States