Date Published:
            2008
      
Publication Type:
            Journal Article
      
Authors:
Secondary:
            AIDS Research and Human Retroviruses
      
Volume:
24
Pagination:
375-8
URL:
            https://pubmed.ncbi.nlm.nih.gov/
      
Keywords:
      
              Adolescent;Adult;Aged;External;Female;HIV Infections;Humans;Middle Aged;Substance P
          
  
Abstract:
            <p>Substance P and its receptor (neurokinin-1R) are potent modulators of neuroimmunoregulation and HIV/AIDS infection. We previously demonstrated that HIV-seropositive men had significantly higher substance P levels compared to uninfected controls. We now demonstrate that substance P plasma levels are significantly higher in HIV-infected women in comparison to uninfected control women.</p>