Date Published:
2018 08

Publication Type:
Journal Article

Authors:

J. Hellmuth
B. Milanini
E. Masliah
M.Carmela Tartaglia
M.B. Dunlop
D.J. Moore
S. Javandel
S. DeVaughn
V. Valcour

Secondary:
Neurocase

Volume:
24

Pagination:
213-219

Issue:
4

PMID:
30304986

URL:
https://pubmed.ncbi.nlm.nih.gov/30304986

DOI:
10.1080/13554794.2018.1530362

Keywords:
Aged, 80 and over;AIDS Dementia Complex;Alzheimer Disease;Brain;Humans;Magnetic Resonance Imaging;Male;Neuropsychological Tests

Abstract:
<p>We discuss the challenges associated with diagnosing neurodegenerative disorders in older adults living with HIV, illustrated through a case report where neurologic co-diagnosis of Alzheimer's disease (AD) and HIV-associated Neurocognitive Disorder (HAND) are considered. The patient was followed and evaluated for over 4 years and underwent post-mortem neuropathologic evaluation. Further work is needed to identify diagnostic tests that can adequately distinguish HAND from early stage neurodegenerative disorders among older adults living with HIV and cognitive changes.</p>