Global NeuroAIDS roundtable.

TitleGlobal NeuroAIDS roundtable.
Publication TypeJournal Article
Year of Publication2013
AuthorsJoseph, J, Achim, C, Boivin, MJ, Brew, BJ, Clifford, DB, Colosi, DA, Ellis, RJ, Heaton, RK, Gallo-Diop, A, Grant, I, Kanmogne, GD, Kumar, M, Letendre, S, Marcotte, TD, Nath, A, Pardo, C, Paul, RH, Pulliam, L, Robertson, K, Royal, W, Sacktor, N, Sithinamsuwan, P, Smith, DM, Valcour, V, Wigdahl, B, Wood, C
JournalJ Neurovirol
Volume19
Issue1
Pagination1-9
Date Published2013 Feb
ISSN1538-2443
KeywordsAIDS Dementia Complex, Global Health, Health Services Needs and Demand, Humans, Neuropsychological Tests
Abstract

In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the "Global NeuroAIDS Roundtable" in conjunction with the 11th International Symposium on Neurovirology and the 2012 Conference on HIV in the Nervous System. The meeting was held in New York, NY, USA and brought together NIMH-funded investigators who are currently working on projects related to the neurological complications of AIDS (NeuroAIDS) in Africa, Asia, Eastern Europe, and Latin America in order to provide an opportunity to share their recent findings and discuss the challenges encountered within each country. The major goals of the roundtable were to evaluate HIV-associated neurocognitive impairment and determine if it may be directly attributable to distinct HIV subtypes or clades and to discuss the future priorities for global NeuroAIDS research. At the "Global NeuroAIDS Roundtable", presentations of preliminary research indicated that HIV-associated neurocognitive impairment is prevalent in all countries examined regardless of which HIV clade is present in the region. The only clear-cut difference between HIV-1 clades was in relation to subtypes A and D in Uganda. However, a key point that emerged from the discussions was that there is an urgent need to standardize neurocognitive assessment methodologies across the globe before definitive conclusions can be drawn regarding the relationship between HIV clade diversity and neuropathogenesis. Future research directions were also discussed at the roundtable with particular emphasis on the potential of viral and host factor molecular interactions to impact the pathophysiology of HIV-associated neurocognitive disorders (HAND) from a global perspective.

DOI10.1007/s13365-012-0143-9
Alternate JournalJ. Neurovirol.
PubMed ID23354550
PubMed Central IDPMC3713197
Grant ListMH073433 / MH / NIMH NIH HHS / United States
MH076651 / MH / NIMH NIH HHS / United States
MH077487 / MH / NIMH NIH HHS / United States
MH078748 / MH / NIMH NIH HHS / United States
MH080611 / MH / NIMH NIH HHS / United States
MH080612 / MH / NIMH NIH HHS / United States
MH083465 / MH / NIMH NIH HHS / United States
MH083489 / MH / NIMH NIH HHS / United States
MH083573 / MH / NIMH NIH HHS / United States
MH085604 / MH / NIMH NIH HHS / United States
MH086356 / MH / NIMH NIH HHS / United States
MH092225 / MH / NIMH NIH HHS / United States
MH094159 / MH / NIMH NIH HHS / United States
MH094160 / MH / NIMH NIH HHS / United States
NS055628 / NS / NINDS NIH HHS / United States
NS055653 / NS / NINDS NIH HHS / United States
P30 MH062512 / MH / NIMH NIH HHS / United States
R01 CA075903 / CA / NCI NIH HHS / United States
R01 DA019807 / DA / NIDA NIH HHS / United States
R01 MH086356 / MH / NIMH NIH HHS / United States
R01 NS074903 / NS / NINDS NIH HHS / United States
U01 MH083506 / MH / NIMH NIH HHS / United States
U24 MH100928 / MH / NIMH NIH HHS / United States